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Umbilical Cords and Placentas Treating HIV, Cerebral Palsy, Cancers, and More

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What can stem cells from the umbilical cord, tissue, and placenta be used to treat?

Patients can request the release of stem cells from an umbilical cord blood bank like Anja Health to a physician overseeing the treatment. Treatment occurs via an IV of the entire bag of cord blood stem cells or localized injections.

Cord blood, tissue, and placenta stem cells can be used to:

  • Improve motor skills in children with cerebral palsy
  • Reverse Type 1 Diabetes
  • Promote protective effects on hair loss
  • Show promise as heart failure treatment
  • Significantly improve symptoms of Crohn's disease, an inflammatory bowel syndrome
  • Used to treat neurological and immune disorders (placenta, specifically)
  • Treating acne scars (placenta, specifically)
  • Treating leukemia
  • Promote CAR T-cell therapy, which is an immunotherapy that fights cancer
  • Immune cell therapy

How we maximize stem cell count

We use manual processing to process our stem cells. Manual processing is handled in the lab by trained technicians rather than a machine. Manual processing is utilized by Anja Health because in the case that very minimal samples are collected (i.e. <40 mL of cord blood), the lab technicians can customize procedures as needed in order to maximize stem cell preservation.

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Cord blood is an FDA-approved treatment for 85+ diseases including numerous types of malignancies, anemias, inherited metabolic disorders and deficiencies of the immune system.
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There are also 1000+ clinical trials looking at other use cases.

Clinical Trials by Therapeutic Category

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58% (598) of all current clinical trials are in oncology, including leukemia, lymphoma, and cancers of the brain, breast, bladder, cervix, colon, esophagus, ovaries, pancreas, and others.

7% (67) are in cardiovascular disorders, including congestive heart failure, myocardial infarction, critical limb ischemia, heart disease, and others.

6% (58) are in musculoskeletal disorders, including spinal muscular atrophy, osteoarthritis, muscular dystrophies, cartilage defects, and bone fractures and disorders, and others.

Neurological & Other Disorders

  • Cartilage–Hair Hypoplasia
  • Günther Disease (Congenital Erythropoietic Porphyria)
  • Hermansky–Pudlak Syndrome
  • Pearson’s Syndrome
  • Shwachman–Diamond Syndrome
  • Systemic Mastocytosis
  • Adrenoleukodystrophy (ALD) / Adrenomyeloneuropathy (AMN)
  • Krabbe Disease (Globoid Cell Leukodystrophy)
  • Metachromatic Leukodystrophy
  • Pelizaeus–Merzbacher Disease
  • Gaucher Disease
  • Niemann–Pick Disease
  • Sandhoff Disease
  • Wolman Disease
  • Lesch–Nyhan Syndrome

Lymphomas & Leukemias

  • Hodgkin’s Lymphoma
  • Neuroblastoma
  • Medulloblastoma
  • Retinoblastoma
  • Acute Lymphoblastic Leukemia
  • Acute Myelogenous Leukemia (AML)
  • Chronic Lymphocytic Leukemia (CLL)
  • Juvenile Chronic Myelogenous
  • Leukemia (JCML)
  • Juvenile Myelomonocytic Leukemia (JMML)
  • Refractory Anemia (RA)
  • Refractory Anemia with Ringed Sideroblasts (RARS)
  • Refractory Anemia with Excess Blasts (RAEB)
  • Refractory Anemia with Excess Blasts in Transformation (RAEB-T)
  • Chronic Myelomonocytic Leukemia (CMML)
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See below why you should bank cord blood

Immune Disorders

  • Epstein–Barr Virus Susceptibility
  • SCID with Adenosine Deaminase Deficiency (ADA-SCID)
  • SCID which is X-linked
  • SCID with absence of T & B Cells
  • SCID with absence of T Cells, Normal
  • B CellsOmenn Syndrome
  • Kostmann Syndrome
  • Ataxia–Telangiectasia
  • Bare Lymphocyte Syndrome
  • Common Variable Immunodeficiency
  • DiGeorge Syndrome
  • Leukocyte Adhesion Deficiency
  • Lymphoproliferative Disorders (LPD)
  • Wiskott–Aldrich Syndrome
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Metabolic & Genetic Disorders

  • Chediak–Higashi Syndrome
  • Neutrophil Actin Deficiency
  • Reticular Dysgenesis
  • Mucopolysaccharidoses (MPS)
  • Hurler’s Syndrome (MPS–IH)
  • Scheie Syndrome (MPS–IS)
  • Hunter’s Syndrome (MPS–II)
  • Sanfilippo Syndrome (MPS–III)
  • Morquio Syndrome (MPS–IV)
  • Maroteaux–Lamy Syndrome (MPS–VI)
  • Sly Syndrome, Beta–Glucuronidase Deficiency (MPS–VII)
  • Mucolipidosis II (I–cell Disease)
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Blood Disorders & Anemia

  • Aplastic Anemia
  • Congenital Dyserythropoietic Anemia
  • Fanconi Anemia
  • Sickle Cell Disease
  • Beta Thalassemia Major (Cooley’s Anemia)
  • Blackfan-Diamond Anemia
  • Pure Red Cell Aplasia
  • Myeloproliferative Disorders
  • Acute Myelofibrosis
  • Agnogenic Myeloid Metaplasia (Myelofibrosis)
  • Polycythemia Vera
  • Essential Thrombocythemia

What happens if I don't bank cord blood,cord tissue, or the placenta?

You will have to use a random donor's cord blood. The chances of survival are much higher if your donor is a relative - especially if you are the donor yourself

A donor's hematopoietic stem cells could be rejected, which could be fatal. Being related to the donor or being the donor yourself increases chances of survival.
On top of that, using a donor's stem cells are exorbitantly more expensive than banking umbilical cord blood.

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Source: New England Journal of Medicine
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Source: The Niche, ipscell.com

Finding a donor can be expensive

Using a donor's stem cells are exorbitantly more expensive than banking umbilical cord blood.

If you're a person of color or mixed race, your chances of finding a donor might be slim

Saving your own stem cells gives you access whenever you may need them. A patient's probability of finding a matching bone marrow donor or cord blood unit on the Be The Match Registry® varies, ranging from 29% to 79% based on their ethnic background.

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Source: Source: Be The Match
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Stem cells can potentially be useful for your whole family.

Saving your own baby's stem cells guarantees at least a partial match for family members.
Some diseases can be treated using the baby's own cord blood (allogeneic use) since they are 100% match! Biological family members can benefit as well.

Data shows that in the next 18 years, 1 in 16 children may need stem cells to better their quality of life.

This information was gained by adding figures from childhood incidence of diseases and extrapolation based on the 18-year figure (multiplying some annual figures by 18 to reach the number). The chart below shows the amount of children by disease in 18 years.

* Every source is linked in the numbers of each disease (Numbers in 18 years)
DiseasesNumbers in 1 yearNumbers in 18 years *
Cancer
3,500 children
63,000 children
Leukemia
353,000 children currently
116,000 children
Aplastic Anemia
216 children
3,900 children
Diamond-Blackfan Anemia
35 children
More than 600 children
Fanconi Anemia
20 children
360 children
Sickle Cell Disease
Affects 1 out of every 500 African-American and 1 in every 1,000 Hispanic newborns
21,945 (African-American), 17,991 (Hispanic)
Langerhans Cell Histiocytosis
8 children
144 children
SCID
100 children
1800 children
Wiskott-Aldrich Syndrome
10 per million males
367 children
Krabbe Disease
1 in 100,000 people
738 children
Hurler Syndrome
1 in every 100,000 babies born
738 children
Metachromatic Leukodystrophy
1 in 40,000 individuals
1,845 children
Sanfilippo Syndrome
1 in 70,000 births
1,054 children

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